Chen, Ming-Shun

Ming-Shun Chen

USDA Research Entomologist,

KSU-adjunct Professor

123 Waters Hall
Manhattan Kansas 66506

Phone: 785-532-4719

Lab links:


Area(s) of Specialization:

Genomics, Proteomics, Plant Defense, Parasite Effectors

View My Curriculum Vitae



B.S. Plant Protection, Hunan Agricultural University, 1981
M.S. Entomology, Fujian Agricultural University, 1984
Ph.D. Biochemistry, Kansas State University, 1991

Research Focus:

Molecular interactions between plant and parasites, Host plant resistance, Effectors and effector-triggered signaling pathways, wheat breeding and gene editing

Selected publications (as of 2022, Total publications 173, H-index 42)


  1. Wei HY, Ye YX, Huang HJ, Chen MS, Yang ZX, Chen XM, Zhang CX (2022) Chromosome‐level genome assembly for the horned-gall aphid provides insights into interactions between gall-making insect and its host plant. Ecology and evolution 12 (4), e8815
  2. Xu Y, La G, Fatima N, Liu Z, Zhang L, Zhao L, Chen MS, Bai G (2021) Precise mapping of QTL for Hessian fly resistance in the hard winter wheat cultivar 'Overland'. Theoretical and Applied Genetics 134 (12): 3951-3962.
  3. Lu Q, Chen X, Yang Z, Bashir NH, Liu J, Cui Y, Shao S, Chen MS, Chen H (2021) Molecular and Histologic Adaptation of Horned Gall Induced by the Aphid Schlechtendalia chinensis (Pemphigidae). International Journal of Molecular Science 22(10): 5166.
  4. Chen H, Lu Q, Chen X, Ling X, Liu P, Liu N, Wang W, Zhang J, Qi Q, Ding W, Zhang X, Feng Y, Zhang Y, Chen MS, King-Jones K (2021) Genome assembly and methylome analysis of the white wax scale insect provides insight into sexual differentiation of metamorphosis in hexapods. Molecular Ecology Resources 21(6): 1983-1995.
  5. Al-jbory ZA, Aikins MJ, Park Y, Reeck GR, Chen MS (2020) Differential localization of Hessian fly candidate effectors in resistant and susceptible wheat plants. Plant Direct 4(8): e0046.
  6. Chen X, Yang Z, Chen H, Qi Q, Liu J, Wang C, Shao S, Lu Q, Li Y, Wu H, King-Jones K, Chen MS (2020) A complex nutrient exchange between a gall forming aphid and its plant host. Frontiers in Plant Science 11:811.
  7. Zhu L, Yuan J, O’Neal J, Brown D, Chen MS (2020) Analyzing molecular basis of heat-induced loss of wheat resistance to Hessian fly (Diptera: Cecidomyiidae) infestation using RNA-sequencing. Journal of Economic Entomology 113 (3): 1504-1512.
  8. Cheng X, Graces-Carrera S, Whitworth RJ, Fellers JP, Park Y, Chen MS (2020) A horizontal gene transfer led to the acquisition of a fructan metabolic pathway in a gall midge. Advanced Biosystem. 4(4): e1900275.
  9. Andreas P, Kisiala A, Emery RJN, De Clerck-floate RM, Tooker JF, Price PW, Miller DG, Chen MS, Connor EF (2020) Cytokinins are abundant and widespread among insect species. Plants 9(2): 208;
  10. Al-jbory ZA, El-Bouhssini M, Chen MS (2018) Conserved and unique putative effectors expressed in the salivary glands of three related gall midge species. Journal of Insect Science. 18 (5): 15 (1-9).
  11. Wang A, Ge JQ, Chen H, Cheng X, Yang Y, Li J, Whitworth RJ, Chen MS (2018) An insect nucleoside disphosphate kinase (NDK) functions as an effector protein in wheat-Hessian fly interactions. Insect Biochemistry and Molecular Biology. 100: 30-38.
  12. Tang G, Liu X, Chen GH, Whitworth RJ, Chen MS (2018) Increasing temperature reduces wheat resistance mediated by major resistance genes to Mayetiola destructor. Journal of Economic Entomology. 111(3): 1433-1438.
  13. Al-jbory Z.A., Anderson K.M., Harris M.O., Mittapalli O., Whitworh R.J. Chen M.S. (2018) Transcriptomic analysis of the secreted proteins from the salivary glands of wheat midge larvae. Journal of Insect Science. 18(1): 17 (1-5).
  14. Chen M.S., Liu S., Wang H., Cheng X., El Bouhssini M., Whitworth R.J. (2016) Genes expressed differentially in Hessian fly larvae feeding in resistant and susceptible plants. J. Mol. Sci. 17 (8): 1324.
  15. Chen M.S., Liu S., Wang H., Cheng X., El Bouhssini M., Whitworth R.J. (2016) Massive shift in gene expression during transitions between developmental stages of the gall midge, Mayetiola destructor. PloS ONE 11(5): e0155616.
  16. Liu X., Zhang S., Whitworth R.J., Stuart J.J., Chen M.S. (2015) Unbalanced activation of glutathione metabolic pathways suggests potential involvement in plant defense against the gall midge Mayetiola destructor. Nature Scientific Report 5: 8092 (doi:10.1038/srep08092)
  17. Chen, M.S., Wheeler, S., Wang, H., Whitworth, R.J. (2014) Impact of temperatures to Hessian fly resistance of selected wheat cultivars in the Great Plains region. Journal of Economic Entomology. 107(3): 1266-1273.
  18. Chen, M.S., Wheeler, S., Davis, H., Whitworth, R.J. Knutson, A., Giles, K.L., Royer, T.A., Skinner, M. (2014) Molecular markers for species identification of Hessian fly males caught on sticky pheromone traps. Journal of Economic Entomology. 107(3):1110-1117.
  19. Bansal, R., Hulbert, S.H., Reese, J.C., Whitworth, R.J., Stuart, J.J., Chen, M.S. (2014) Pyrosequencing reveals the predominance of Pseudomonadaceae in gut microbiome of a gall midge. Pathogens 3(2): 459-472.
  20. Li C., Chen M.S., Chao S., Yu J., Bai G. (2013) Identification of a novel Hessian fly resistance gene, H34, in wheat using recombinant inbred lines and single nucleotide polymorphism markers. Theoretical and Applied Genetics. 126 (8): 2065-2071.
  21. Khajuria C., Wang H., Liu X., Wheeler S., Reese J.C., El Bohssini M., Whitworth R.J., Chen M.S. (2013) Mobilization of lipids and fortification of cell wall and cuticle are important in host defense against Hessian fly. BMC Genomics 14: 423.
  22. Liu X.M, Khajuria C., Li J., Trick H.N., Huang L., Gill B.S., Reeck G.R., Antony G., White F.F., Chen M.S. (2013) Wheat Mds-1 encodes a heat-shock protein and governs susceptibility towards the Hessian fly gall midge. Nature Communication. 4: 2070.
  23. Chen H., Zhu Y.C., Whitworth R.J., Reese J.C., Chen M.S. (2013) Serine and cysteine protease-like genes in the genome of a gall midge and their interactions with host plant genotypes. Insect Biochemistry and Molecular Biology. 43: 701-711.
  24. Tan T.T., Carver B.F., Chen M.S., Gu Y.Q., Yan L. (2013) Genetic association of OPR genes with resistance to Hessian fly in hexaploid wheat. BMC Genomics. 14:369.
  25. Martin T.J., Zhang G.,Fritz A.K., Miller R., Chen, M.S. (2013) Registration of ‘Tiger” wheat. Journal of Plant Registration 7(2): 201-204.
  26. Khajuria C., Williams C., J.C., El Bohssini M., Whitworth R.J., Richards S., Stuart J.J., Chen M.S. (2013) Deep Sequencing and Genome-wide Analysis Reveals the Expansion of MicroRNA Genes in the Gall Midge Mayetiola Destructor. BMC Genomics 14: 187.