- 107C Waters Annex
- ksilver@ksu.edu
- 785-532-4752
Education
- 1999-2005 Ph.D. Environmental Toxicology, Cornell University, Ithaca, New York.
- 1995-1999 B.S. Biology, Moravian College, Bethlehem, PA.
Research Interests
My research interests broadly encompass the physiological and molecular interactions between insects and insecticides. Particular emphasis is currently on mechanisms of RNA interference and uptake of double-stranded RNA in addition to insecticides targeting voltage-gated sodium channels.
Recent Publications
Silver, KS, B. Zhorov, K. Dong. 2017. Molecular mechanism of action and selectivity of sodium channel blocker insecticides. Current Medicinal Chemistry 23. Epub.
Silver, KS, A Littlejohn, L Thomas, E Marsh, JD Lillich. 2015. Inhibition of Kv channel expression by NSAIDs depolarizes membrane potential and inhibits cell migration. Biochemical Pharmacology 98: 614-628.
Silver, KS, H Jiang, JP Fu, TW Phillips, RW Beeman, Y Park. 2014. The Tribolium castaneum cell line, TcA:a new tool kit for cell biology. Scientific Reports 4: 6840.
Dong, K, Y Du, F Rinkevich, Y Nomura, P Xu, L Wang, KS Silver, BS Zhorov. 2014. Molecular Biology of Insect Sodium Channels and Pyrethroid Resistance. Insect Biochemistry and Molecular Biology.50: 1-17.
Silver, KS, Y Du, Y Nomura, EE Oliviera, VL Salgado, B Zhorov, K Dong. 2014. Voltage-gated sodium channels as insecticide targets. In E. Cohen, editor: Target receptors in the control of insect pests: Part II, Vol 46, Advances in Insect Physiology, UK: Academic Press, p. 389-433.
von Stein, F, KS Silver, DM Soderlund. 2013. Indoxacarb, Metaflumizone, and Other Sodium Channel Inhibitor Insecticides: Mechanism and Site of Action on Mammalian Voltage-Gated Sodium Channels. Pesticide Biochemistry and Physiology 106: 101-112.
Goodman CL, D Stanley, JA Ringbauer Jr, RW Beeman, KS Silver, Y Park. 2012. A cell line derived from the red flour beetle Tribolium castaneum (Coleoptera: Tenebrionidae). In Vitro Cellular & Developmental Biology – Animal48: 426-433.
Silver, KS, A Desourmaux, LC Freeman, and JD Lillich. 2012. Expression of pleiotrophin, an important regulator of cell migration, is inhibited in intestinal epithelial cells by treatment with non-steroidal anti-inflammatory drugs. Growth Factors 30: 258-266.
Lillich, JD, W Ray-Miller, KS Silver, E Davis, and BD Schultz. 2011. Intra-abdominal hyaluronan concentration in peritoneal fluid of horses with sudden signs of severe abdominal pain. American Journal of Veterinary Research. 72: 1666-1673.
Song, W, KS Silver*, Y Du, Z Liu, K Dong. 2011. Analysis of the action of lidocaine on insect sodium channels. Insect Biochemistry and Molecular Biology 41: 36-41.
Silver, KS, L Leloup, LC Freeman, A Wells, JD Lillich. 2010. Non-steroidal anti-inflammatory drugs inhibit calpain activity and membrane localization of calpain 2 protease. International Journal of Biochemistry and Cell Biology 42: 2030-2036.
Silver, KS, W Song, Y Nomura, V Salgado, K Dong. 2010. Mechanism of action of sodium channel blocker insecticides (SCBIs) on insect sodium channels. Pesticide Biochemistry and Physiology 97: 87-92.