Kansas State University

Department of Entomology
123 W. Waters Hall
Kansas State University
Manhattan KS 66506-4004

 

785-532-6154
785-532-6232 fax

entomology@k-state.edu

 

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Park-Yoonseong

Park-Yoonseong

Professor
32 W. Waters Hall
Manhattan KS 66506
Phone: (785) 532-5763
Fax: (785) 532-6232
ypark@ksu.edu
Link to Park Lab

Education

B.S. Agricultural Biology, Chonbuk National University, Korea, 1991
M.S. Entomology, University of California, Riverside, 1994
Ph.D. Insect Science, University of Arizona, Tuscon, 1998
Post Doctoral Associate , University of California, Riverside, 1998 - 2002

Teaching

  • Insect Physiology [ENTOM 875]
  • Insect Morphology [ENTOM 866]

Research

1. Arthropod signaling peptides and their receptors.

The peptide signaling system, an ancient cell-cell communication mechanism, appears to be the top upstream commands that modulate various behavioral and physiological events. My research focuses on evolution of neuropepetides, their receptors, and functions. Model arthropods that we study are the species fruitfly (Drosophila melanogaster), red flour beetle (Tribolium castaneum), and blacklegged tick (Ixodes scapularis).

2. Signaling pathways for tick salivary secretion.

Ticks are obligatory ectoparasites that feed on the blood of vertebrate hosts and often transmit pathogens, including bacteria, protozoa, and viruses. The salivary secretions of ticks play an important role in blood feeding by modulating the host response. We investigate neural and hormonal mechanisms controlling salivary secretion, involving multiple neuropeptides and catecholamines.



Publications

 

 Wang, J.  , G. S. Simmons, T. A. Miller, B. E. Tabashnik, Y. Park (2011) Global Variation in the piggyBac-like Element of Pink Bollworm,

 

Lu, Y., Y.-P. Pang, Y. Park, X. Gao, J. Yao, X. Zhang, and K. Y. Zhu. 2011. Genome organization, phylogenies, expression patterns and three-dimensional protein models of two acetylcholinesterase genes from the red flour beetle. PLoS ONE (under revision).

 

Kim, H. S., T. Murphy, J. Xia, D. Caragea, Y. Park, R. Beeman, M. Lorenzen, J. Manak, S. Butcher, and S. Brown (2010) BeetleBase in 2010: revisions to provide comprehensive genomic information for Tribolium castaneum. Nucleic Acid Research 38: D437-D442.

 

Shrestha,, S., Y. Park, D. Stanley, Y. Kim (2010) Genes encoding phospholipases A2 mediate insect nodulation reactions to bacterial challenge. J. Insect Phys. 56 324-332.

 

Paluzzi, J-P., Y. Park, R. J. Nachman, and I. Orchard (2010) Isolation, expression analysis, and functional characterization of the first antidiuretic hormone receptor in insects. Proc. Nat. Aca. Sci. USA. 107: 10290-10295.

 

Wang, J., E. D. Miller, G. S. Simmons, T. A. Miller, B. E. Tabashnik, Y. Park  (2010) PiggyBac-like elements in the pink bollworm, Pectinophora gossypiella.  Insect Molec. Biol. 19: 177-184


Arakane, Y., R. Dixut, K. Begum, Y. Park, C. A. Specht, H. Merzendorfer, K. J. Kramer, S. Muthukrishnan, R. W. Beeman (2009) Analysis of functions of the chitin deacetylase gene family in Tribolium castaneum. Insect Biochem. Mol. Biol. 39: 355-365.

Ladislav R., I. Žitanová, L. Dai, L. Šimo, Y. Park, H. Satake, Y. Tanaka, M. E. Adams, and D. Žitnan (2009) Ecdysis triggering hormone signaling in arthropods. Peptides 31: 429-441.

 

Begum, K., B. Li, R. W. Beeman, and Y. Park (2009) Functions of ion transport peptide and ion transport peptide-like in the red flour beetle Tribolium castaneum. Insect Biochem. Mol. Biol. 39: 717-725.

 

Šimo, L., M. Slovák, Y. Park and D. Žitnan (2009) Identification of a complex peptidergic neuroendocrine network in the hard tick, Rhipicephalus appendiculatus. Cell and Tissue Research 335: 639-655.

 

 

 Šimo, L., D. Žitnan, and Y. Park (2009) Two novel neuropeptides in innervation of the salivary glands of the blacklegged tick Ixodes scapularis: Myoinhibitory peptides and SIF amide. Journal of Comparative Neurology. 517: 551-563.


Park, Y., and Richard W. Beeman (2008) Postgenomics of Tribolium: targeting the endocrine regulation of diuresis. Entomological Research. 38:93-100.
Arakane, Y., B. Li, S. Muthukrishnan, R. W. Beeman, K. J. Kramer, and Y. Park(2008) Functional analysis of four neuropeptides, EH, ETH, CCAP and bursicon, and their receptors in adult ecdysis behavior of the red flour beetle, Tribolium castaneum.

Li, B., R. Predel, S. Neupert, F. Hauser, Y. Tanaka, G. Cazzamali, M. Williamson, P. Verleyen, L Schoofs, J. Schachtner, C. J. P. Grimmelikhuijzen, and Y. Park (2008) Genomics, transcriptomics, and peptidomics of peptide and protein hormones in the red flour beetle Tribolium castaneum. Genome Research 18: 113-122

 

Lorenzen, M. D. , A. Gnirke, J. Margolis, M. Campbell, J. J. Stuart, S. Richards, Y. Park, and R. W. Beeman (2008) The maternal-effect, selfish genetic element Medea in Tribolium is a Tc1 transposon. Proc. Nat. Aca. Sci. USA. 105:10085-10089.

 


Siebert, K., M. D. Lorenzen, S. J. Brown, Y. Park, and R. W. Beeman (2008) Tubulin superfamily genes in Tribolium castaneum, and use of a Tubulin promoter to drive transgene expression. Insect Biochem. Mol. Biol. 38: 749-755.

Tribolium Genome Sequencing Consortium 2008. The genome of the model beetle and pest Tribolium castaneum. Nature 452:949-955.



Aikins, J. M., D. A. Schooley, K. Begum, R. W. Beeman, and Y. Park (2008) Vasopressin-like peptide and its receptor function in an indirect diuretic signaling pathway in the red flour beetle. Insect Biochem. Mol. Biol. 38: 740-748.

Hauser, F., G. Cazzamali, M. Williamson, Y. Park, B. Li, Y. Tanaka, R. Predel, S. Neupert, J. Schachtner, P. Verleyen and C. J. P. Grimmelikhuijzen (2008) A genome-wide inventory of neurohormone GPCRs in the red flour beetle Tribolium castaneum. Frontiers in Neuroendocrinology 29: 142-165

 

Wang J., C-C., W., S. Brown, and Y. Park.  2008.  Large diversity of piggyBac-like elements in the genome of Tribolium castaneum. Insect Biochemistry and Molecular biology 38: 490-498

 

Park, Y. J. Aikins, L.J. Wang, R. W. Beeman, B. Oppert, J. C. Lord, S. J. Brown, M. D. Lorenzen, S. Richards, G M. Weinstock, and R A. Gibbs.  2008.  Analysis of transcriptome data in the red flour beetle Tribolium castaneum. Insect Biochemistry and Molecular biology 38: 380-386


Mutti, N. S., J. Louis, L. K. Pappan, K. Pappan, K. Begum, M-S. Chen, Y. Park, N. Dittmer, J. Marshall, J. C. Reese and G. R. Reeck (2008) A novel protein from the salivary glands of the pea aphid, Acyrthosiphon pisum, is essential in feeding on host plants. Proc. Nat. Aca. Sci. USA. 105: 965-9969

Adams, M. E., Y-J. Kim, Y. Park, and D. Zitnan (2006) Developmental peptides: ETH, corazonin and PTTH. In Handbook of biologically active pe

 

Wang, J.J., T.A. Miller, and Y.S. Park.  2006. Development of multiple dominant markers by using Vectorette PCR-based nonradioactive transposable element display.  Molecular Ecology Notes 6:642-645. 

 

Wang, J., X. Ren, T.A. Miller and Y. Park.  2006.  pibbyBac-like elements in the tobacco budworm, Heliothis virescens (Fabricius).  Insect Molecular Biology 15: 435-443

 

Maddur, A.A., X. Liu, Y.C. Zhu, J.P. Fellers, B. Oppert, Y. Park, J. Bai, G.E. Wilde and M.S. Chen.  2006.  Cloning and characterization of protease inhibitor-like cDNAs from the Hessian fly Mayetiola destructor (SAY).  Insect Molecular Biology 15: 485-496.

 

Konakandla, B, Y. Park and D.C. Margolies. 2006. Whole gene amplification of Chelix-extracted DNA from a single mite: A method for studying genetics of the predatory mite Phytoseiulus persimilis. Experimental and Applied Acarology 40:241-247.

 

Mutti, N. S., Y. Park, J. C. Reese, and G. R. Reeck. 2006. RNAi knockdown of a salivary transcript leading to lethality in the pea aphid, Acyrthosiphon pisum. J. Insect Science 6:38.  

 

Wang, J., R. Staten, T.A. Miller and Y. Park.  2005.  Inactivated mariner-like elements (MLE) in pink bollworm, Pectinophora gossypiella.  Insect Molecular Biology 14: 547-553

 

Beeman, R.W., S.J. Brown, M.D. Lorenzen and Y. Park.  2005.  Tribolium genomics: sleuthing for novel targets.  Abstracts of papers of the American Chemical Society 228: U85-U85 016-AGRO part 1, Aug. 22, 2004

 

Kim, Y. Spalivska-Valachova, J., Cho, J-H., Zitanova, I, Park, Y., Adams, M.E. and Zitnan, D.  2004.  Corazonin receptor signaling in ecdysis initiation.  Proceedings of the National Academy of Sciences of the United States of America 101: 6704-6709.

 

Park, Y., Kim, Y-J., Dupriez, V., and Adams, M. E. (2003) Two subtypes of ecdysis-triggering hormone receptor in Drosophila melanogaster, Journal of Biological Chemistry 278: 17710-17715

 

Zitnan, D., Zitnanova, I, Spalovska, I., Takac, P., Park, Y., and Adams, M. E. (2003) Conservation of ecdysis triggering hormone signaling in insects. Journal of Experimental Biology 206: 1275-1289.

 

Park, Y., Kim, Y-J., and Adams, M. E. (2002) Identification of G protein-coupled Receptors for Drosophila PRXamide peptides, CCAP, Corazonin, and AKH Supports a Theory of Ligand-Receptor Co-evolution. Proceedings of the National Academy of Sciences of the United States of America 99: 11423-11428.

 

Park, Y., Filippov, V., Gill, S. S. and Adams, M. E. (2002) Lethal behavioral deficit following deletion of a peptide hormone gene. Development. 129: 493-503.

 

Loi, P.K., Emmal, S.A., Park, Y., and Tublitz, N.J. (2001) Identification, sequence and expression of a Crustacean Cardioactive Peptide (CCAP) gene in the moth Manduca sexta. Journal of Experimental Biology 204: 2803-2816.

 

Park, Y., Lee, D., Taylor, M. F. J., Holloway, J., Ottea, J. A., Adams, M. E., and Feyereisen, R. (2000) Characterization of L1029H mutation in the sodium channel for pyrethroid resistance in Heliothis virescens F. Pestic. Biochem. Physiol. 66: 1-8.

 

Zhao. Y, Park, Y., Adams, M. E. (2000) Functional and evolutionary consequences of pyrethroid resistance mutations in S6 transmembrane segments of a voltage-gated sodium channel. Biochem. Biophys. Res. Comm. 278:516-521

 

Park, Y., Zitnan, D., Gill, S. S., and Adams, M. E. (1999) Molecular cloning and biological activity of ecdysis triggering hormone (ETH) in Drosophila melanogaster. FEBS Letters 463: 133-138.

 

Lee, D., Park, Y., Brown, T. M., Adams, M. E. (1999) Altered property of neuronal sodium channels associated with resistance to pyrethroid insecticide. Molec. Pharmacol. 55: 584-593


Park, Y., Taylor, M. F. J., and Feyereisen, R. (1999) Genomic structure of para homologous voltage-gated sodium channel in Heliothis virescens F. Insect Molec. Biol. 8: 162-170.